Detalhe da pesquisa
1.
Lifetime Stressful Events Associated with Alzheimer's Pathologies, Neuroinflammation and Brain Structure in a Risk Enriched Cohort.
Ann Neurol
; 2024 Mar 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-38466157
2.
Genotypic effects of APOE-ε4 on resting-state connectivity in cognitively intact individuals support functional brain compensation.
Cereb Cortex
; 33(6): 2748-2760, 2023 03 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-35753703
3.
Genetic characterization of the ALFA study: Uncovering genetic profiles in the Alzheimer's continuum.
Alzheimers Dement
; 20(3): 1703-1715, 2024 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-38088508
4.
Risk of cognitive decline progression is associated to increased blood-brain-barrier permeability: A longitudinal study in a memory unit clinical cohort.
Alzheimers Dement
; 20(1): 538-548, 2024 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-37727082
5.
Astrocyte biomarkers GFAP and YKL-40 mediate early Alzheimer's disease progression.
Alzheimers Dement
; 20(1): 483-493, 2024 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-37690071
6.
A novel ultrasensitive assay for plasma p-tau217: Performance in individuals with subjective cognitive decline and early Alzheimer's disease.
Alzheimers Dement
; 20(2): 1239-1249, 2024 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-37975513
7.
A blood-based multi-pathway biomarker assay for early detection and staging of Alzheimer's disease across ethnic groups.
Alzheimers Dement
; 20(3): 2000-2015, 2024 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-38183344
8.
Age, sex and APOE-ε4 modify the balance between soluble and fibrillar ß-amyloid in non-demented individuals: topographical patterns across two independent cohorts.
Mol Psychiatry
; 27(4): 2010-2018, 2022 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35236958
9.
Memory performance mediates subjective sleep quality associations with cerebrospinal fluid Alzheimer's disease biomarker levels and hippocampal volume among individuals with mild cognitive symptoms.
J Sleep Res
; : e14108, 2023 Nov 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-38035770
10.
Differential effects of sleep on brain structure and metabolism at the preclinical stages of AD.
Alzheimers Dement
; 19(12): 5371-5386, 2023 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-37194734
11.
Plasma and CSF biomarkers in a memory clinic: Head-to-head comparison of phosphorylated tau immunoassays.
Alzheimers Dement
; 19(5): 1913-1924, 2023 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-36370462
12.
Blood-brain barrier integrity impacts the use of plasma amyloid-ß as a proxy of brain amyloid-ß pathology.
Alzheimers Dement
; 19(9): 3815-3825, 2023 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-36919582
13.
Reactive astrogliosis is associated with higher cerebral glucose consumption in the early Alzheimer's continuum.
Eur J Nucl Med Mol Imaging
; 49(13): 4567-4579, 2022 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-35849149
14.
Diagnostic performance and prediction of clinical progression of plasma phospho-tau181 in the Alzheimer's Disease Neuroimaging Initiative.
Mol Psychiatry
; 26(2): 429-442, 2021 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33106600
15.
The BDNFVal66Met SNP modulates the association between beta-amyloid and hippocampal disconnection in Alzheimer's disease.
Mol Psychiatry
; 26(2): 614-628, 2021 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-30899092
16.
Time course of phosphorylated-tau181 in blood across the Alzheimer's disease spectrum.
Brain
; 144(1): 325-339, 2021 02 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-33257949
17.
The FTD-like syndrome causing TREM2 T66M mutation impairs microglia function, brain perfusion, and glucose metabolism.
EMBO J
; 36(13): 1837-1853, 2017 07 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-28559417
18.
Cerebral amyloid-ß load is associated with neurodegeneration and gliosis: Mediation by p-tau and interactions with risk factors early in the Alzheimer's continuum.
Alzheimers Dement
; 17(5): 788-800, 2021 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33663013
19.
White matter hyperintensities mediate gray matter volume and processing speed relationship in cognitively unimpaired participants.
Hum Brain Mapp
; 41(5): 1309-1322, 2020 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31778002
20.
Plasma p-tau181 accurately predicts Alzheimer's disease pathology at least 8 years prior to post-mortem and improves the clinical characterisation of cognitive decline.
Acta Neuropathol
; 140(3): 267-278, 2020 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32720099